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Forty-one persons have been confirmed as infected with the 2009 influenza A(H1N1) at Nakhon Ratchasima Rajanagarindra Psychiatric Hospital, the Ministry of Public Health said, emphasising the situation is however under control.
The patients are being closely monitored for two weeks to ensure that the epidemic will be contained.
Public Health Ministry Inspector General Kamron Chaisiri said the infections were found in the Nakhon Ratchasima facility in the northeast in early June.
Six female and 35 male patients have been admitted, including six who are hospital staff, he said.
According to the initial investigation, one hospital worker became infected with the flu virus through his daughter, who came down with the flu fell on June 8. All members of the family subsequently became infected with the disease.
The hospital detected the first case of flu on June 12 in the ward for alcoholism patients. The ministry official said that such patients have weaker immune systems and are easily infected with disease.
The patients were given the antiviral drug Tamilflu, and none are severely ill, he said, adding that the patients had been separated for better treatment and care.
Kamron said the hospital has temporarily stopped admitting new patients until the situation was confirmed safe, which would be about two weeks, but outpatient services are operating normally.
Health officials have sampled the schools in the province and discovered no other cases of flu.